Short report: Cluster analysis showed long-term cognition can be predicted by looking at regional grey matter atrophy in the ...

Background Traumatic brain injury (TBI) is common in military campaigns and is a risk factor for dementia. ArmeD SerVices TrAuma and RehabilitatioN OutComE-TBI (ADVANCE-TBI) aims to ascertain ...

Background Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral haemorrhage (ICH) with a high recurrence risk. Left atrial appendage occlusion (LAAO) is a method for ischaemic stroke ...

Immune checkpoint inhibitors (ICI) have had a dramatic effect on cancer outcomes with their use increasing as indications expand. Despite impressive efficacy across a range of tumour types, their role ...

Introduction Frequent focal seizures are a hallmark of encephalitis with antibodies to leucine-rich glioma-inactivated 1 (LGI1-Ab-E) in humans. Recently, LGI1-Ab-E has emerged as an important cause of ...

Background The Problem Behaviors Assessment – Short Form (PBA-s) is a widely used measure of behavioral symptoms in HD research given its comprehensiveness and development for use with people with ...

Introduction Gerstmann-Sträussler-Scheinker (GSS) syndrome, caused by the PRNP P102L mutation is cha- racterized by slowly ascending distal lower limb sensory loss, cerebellar ataxia, pyramidal signs, ...

Functional Neurological disorder (FND) is a common, disabling condition which is often seen in Neurology Clinics. There are significant challenges associated with making the diagnosis accurately and ...

Background Functional motor disorders (FMD) cause long-term disability and economic burden. There is a need for multidisciplinary interventions to manage both motor and non-motor symptoms. We aim to ...

Background Disease-modifying therapies (DMTs) for Alzheimer’s disease (AD) have early evidence of efficacy. Widespread delivery of DMTs will require major service reconfiguration. Treatment pathways ...

Background Reports of primary angiitis of the central nervous system (PACNS) are mainly restricted to clinically suspected cases, but biopsy-proven ones are rare. Here, we present results from a large ...