Animal testing remains to be a vital part of modern preclinical testing. While the ethics of the use of animals in medical testing remains keenly debated, it is still generally accepted worldwide and ...

Experimental research in human disease requires the use of controls. This means that more than one subject is required to observe the variable being tested, whilst all other factors must be kept ...

Advances in genome editing have transformed the development of animal models used to understand human diseases. While transgenic mouse models have broadly ...

CRISPR-Cas9 technology is used to knock out or modify DNA in research mice to study disease phenotypes and develop new treatments. CRISPR mice and rats are offered by Charles River, which uses genetic ...