In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the ...
Their findings, published online in Developmental Cell on April 22, focus on how temperature alters key epigenetic signals—chemical tags on DNA-packaging proteins that determine which genes are active ...
Researchers at Lund University in Sweden have created a method that makes it possible to transform the brain’s support cells into parvalbumin-positive cells. These cells act as the brain’s ...
Researchers developed a way to directly reprogram human glial cells into PV interneurons without passing through a stem‑cell stage.
Researchers at Lund University in Sweden have created a method that makes it possible to transform the brain’s support cells ...
A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...
Remains on track to name a development candidate for a novel first-in-class neurology program targeting demyelinating diseases in 2026Progresses discovery work on a best-in-class cell therapeutic ...
Pair showed that adult cells can be reprogrammed to an embryonic state. I think that all Nobel prize winners should sport badass hair like this Gurdon guy. On a more serious note, this is an awesome ...
Parvalbumin cells play a central role in keeping brain activity in equilibrium. They control nervcell signaling, reduce ...
Astrocytes in the adult brain show cellular plasticity; however, whether they have the potential to generate multiple lineages remains unclear. Here, we perform in vivo screens and identify DLX2 as a ...